James T. Perkins, MDDirector, Blood Bank
Director, School of Medical Technology Program

The Evanston Hospital Blood Bank is a “full service” blood bank in that we have both transfusion and donor services.   This allows the resident to experience the full range of transfusion medicine activities, including activities that many hospitals delegate to a blood center.

The transfusion service performs compatibility testing and prepares blood components for transfusion. In our laboratory compatibility testing includes completion of the most complex blood group antibody problems. The laboratory is a member of the Serum, Cells, and Rare Fluids exchange which is a source of special reagents for this immunohematologic testing.  Component preparation performed by  the laboratory includes removal of leukocytes by filtration and of plasma by washing, irradiation (to prevent graft-versus-host disease), aliquoting of red blood cells and plasma for neonates, hematopoietic progenitor cell processing, freezing and storage, and other manipulations as needed.

The donor service has the mission of providing for the special transfusion medicine needs of our patients.  To fulfill that mission we collect autologous and directed donor whole blood, apheresis (“single donor”) platelets, and volunteer whole blood.  We also perform a large number of therapeutic phlebotomies for patients with polycythemia vera and hemochromatosis.

The blood bank director and other laboratory staff work closely with the clinical staff in an attempt to optimize transfusion medicine services.  This includes followup and reporting on all transfusion reactions, frequent consultations on hemostatic component therapy, direct participation in the hematopoietic progenitor cell transplant program and in the care of patients with hemolytic disease of the newborn, and close management of the blood supply in times of shortage.  Tangible positive outcomes of this relationship include a relatively high rate of autologous transfusion at the four NorthShore hospitals, relatively low rates of plasma and platelet usage, reduced donor exposures for neonatal patients, and high rates of satisfaction for the patients and donors with whom the laboratory is in direct contact.


  • American Board of Pathology, Anatomic and Clinical Pathology, 1984
  • American Board of Pathology, Blood Banking and Transfusion Medicine, 1989

University Appointment

  • Clinical Assistant Professor of Pathology, University of Chicago Pritzker School of Medicine

Education and Training

  • 1978, University of Chicago, Pritzker School of Medicine, MD
  • 1978-1979, Cook County Hospital, Internship in Internal Medicine
  • 1979-1984, University of Chicago, Residency in Pathology


  • Perkins JT: Fatal drug-induced immune hemolytic anemia due to cefotetan: A case study.  Asian J Transf Sci 2008; 2:20-3.
  • www.indianinitiative.org
  • Sullivan ME, Carolan A, Perkins JT, Check IJ: Unexpected hemoglobin A results after an erythrocyte exchange: importance of specimen mixing.  Clin Chem 2008; 54(6):1088-90.
  • Woodfield G, Perkins JT, Johnson ST: An immunohematoogical "wet" workshop.  Asian J Transf Sci 2007; 1:77-80.