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Parkinson's Disease & Movement Disorders Clinical Trials

The Longitudinal Clinical and Genetic Study of Parkinson's Disease (LONG-PD Study)
Aims: The clinical and genetic factors that influence motor and non-motor severity, progression and outcomes in Parkinson’s disease are unknown. Identification of these factors may allow us to individualize the care of patients and improve neurological health. The Genetic Epidemiology of Parkinson’s Disease (GEO- PD) consortium clinics care for thousands of patients each year. The purpose of this study is to develop a Web-based platform for the capture and sharing of standardized data that measure motor and non-motor severity, progression and outcomes in Parkinson’s disease across 25 global sites—from 18 countries, 5 continents, 4200 cases. These patients will be followed for 15 years for collaborative research studies. Additionally, DNA will be shared in a central repository to conduct genomic studies of severity, progression and outcomes in Parkinson's disease.
Principal Investigator: Aikaterini Markopoulou, MD, PhD
NorthShore Project Number: EH15-283
Funding Source: NorthShore University HealthSystem
Contact: Call 847.503.4335 with questions regarding the study
Open to enrollment: Yes

Genetic Analysis of Familial Parkinsonism
Aim: The purpose of this study is to identify inherited factors that may cause Parkinson’s disease or Parkinsonism.
Principal Investigator: Aikaterini Markopoulou, MD, PhD
NorthShore Project Number: EH16-166
Contact: Call 847.503.4335 with questions regarding the study 
Open to enrollment: Yes

Synuclein-One Study
Aims: the purpose of this research study is to determine whether small skin biopsies can be used as a novel method of detecting diseases collectively known as synucleinopathies which include Parkinson disease (PD), Multiple System Atrophy (MSA), Dementia with Lewy bodies and Pure Autonomic Failure (PAF). This study will evaluate the effectiveness of this skin biopsy test to confirm a diagnosis of a synucleinopathy and ensure that testing abnormalities are not detected in healthy individuals.
Principal Investigator: Alexandru Barboi, MD
NorthShore Project Number: EH21-081
Contact: Please call 847.503.4333 with questions regarding the study
Open to Enrollment: Yes