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Breast Surgery Trials

Impact of an In-Visit Decision Aid on Uniformed Decison Making for Contralateral Prophylactic Mastectomy
Aims: To determine whether using an online decision intervention directly with patients will increase patient knowledge resulting in less patients making uninformed decisions to undergo contralateral prophylactic mastectomy.
Diagnosis: Breast Cancer- Participants must enroll prior to breast surgery
Principal Investigator: Katherine Yao, MD
IRB Approval Number: EH17-045
Sponsor: NorthShore University HealthSystem
Contact:  Interested patients may contact Sarah Rabbitt, RN, CCRP at 847.570.1681, srabbitt@northshore.org
Open to Enrollment: Yes

The NorthShore Study of Surgical Decision-Making and Quality of Life Outcomes after Breast Cancer Surgery
Aims: To discover the decision-making pathway in newly diagnosed breast cancer patients.
Diagnosis: Breast cancer. Participants must enroll prior to breast surgery.
Principal Investigator: Mark Sisco, MD
IRB Approval Number: EH14-218
Sponsor: NorthShore University HealthSystem
Contact: Interested patients may contact Jen Jaffe, MPH, CCRP 847.570.2803jjaffe@northshore.org
Open to Enrollment: Yes

Using Genetic Risk Scores to Assess the Efficacy of Mammography Screening Among Women Diagnosed with Breast Cancer
Aims: The study is looking at whether one's Genetic Risk Score (GRS) along with other risk factors will aid in identification of a subgroup of women at high risk for breast cancer in need of increased surveillance. 
Diagnosis: Breast Cancer
Principal Investigator: Catherine Pesce, MD
IRB Approval Number: EH15-308
Sponsor: NorthShore University HealthSystem
Contact: Interested patients may contact Sarah Rabbitt, RN, CCRP at 847.570.1681srabbitt@northshore.org or Sandra Simovic at 847.570.4227ssimovic@northshore.org
Open to Enrollment: Yes

A011104: Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women with Breast Cancer
Aims: The purpose of this study is to test whether patients undergoing breast MRI (magnetic resonance imaging) before breast surgery will have better results after the surgery. Breast tumors are routinely evaluated during mammograms and ultrasound before surgery. This study would like to find out if using MRI in addition to mammography before surgery improves our ability to evaluate tumors and decide what kind of surgery is best for the patient.
Diagnosis: Breast Cancer, Clinical Stage I-II
Principal Investigator: Katherine Yao, MD
IRB Approval Number: EH14-346
Sponsor: Alliance for Clinical Trials in Oncology
Contact: Interested patients may contact Sarah Rabbitt, RN at 847.570.1681 srabbitt@northshore.org
Open to Enrollment: Yes

Germline Genetic Profiles Associated with Contralateral Breast Cancer Patients
Aims: To determine whether or not women diagnosed wtih contralateral breast cancer have higher incidences of know breast cancer-risk associated genetic alterations 
Diagnosis: Breast Cancer
Principal Investigator: Katherine Yao, MD
IRB Approval Number: EH16-063
Sponsor: NorthShore University HealthSystem
Contact: Interested patients may contact Sarah Rabbitt, RN at 847.570.1681srabbitt@northshore.org or Sandra Simovic at 847.570.1681, ssimovic@northshore.org
Open to Enrollment: Yes

A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3N1) who have Positive Sentinent Lymph Node Disease After Neoadjuvant Chemotherapy
Aims: This randomized phase III trial studies axillary lymph node dissection to see how well it works compared to axillary radiation therapy in treating patients with node-positive breast cancer treated with neoadjuvant chemotherapy followed by surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in patients with breast cancer. Radiation therapy uses high-energy x-rays to kill tumor cells. This study will evaluate whether radiation therapy is as effective as lymph node dissection. 
Diagnosis: Breast Cancer, Clinical Stage II-IIIA
Principal Investigator: Catherine Pesce, MD
IRB Approval Number: EH15-297
Sponsor: Alliance for Clinical Trials in Oncology
Contact: Interested patients may contact Sarah Rabbitt, RN at 847.570.1681srabbitt@northshore.org
Open to Enrollment: Yes