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Janardan D. Khandekar , MD

Center for Molecular Medicine

Contact Information

 847.733.5294 fax


  • Medical School: 1969, M.B.B.S., MD - University of Indore, India
  • Post-Graduate:

    (1967–1970) Housestaff, M.Y. Hospital, Indore, India

    (1970–1971) Fellow, Medical Research Council, Univ. of Montreal

    (1972–1973) Resident in Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania

    (1973–1975) Fellow in Oncology, Tufts University Hospitals, Boston, Massachusetts

Board Certification

  • 1974 Diplomate, American Board of Internal Medicine
  • 1975 Diplomate, Medical Oncology, American Board of Internal Medicine

Research and Academic Interests

  • Personalized Medicine

Career Summary

  • (1973–1975) Fellow, Tufts University School of Medicine: (Medical Oncology)

  • (1975–1980) Assistant Professor of Medicine, Northwestern University Feinberg School of Medicine

  • (1975–1998) Head, Division of Medical Oncology, NorthShore University HealthSystem

  • (1979–1987) Associate Director, Kellogg Cancer Centers, NorthShore University HealthSystem

  • (1980–1986) Associate Professor of Medicine, Northwestern University Feinberg School of Medicine

  • (1986–2009) Professor of Medicine, Northwestern University Feinberg School of Medicine

  • (1987–1998) Kellogg/Scanlon Chair, NorthShore University HealthSystem
  • (1989–1995) Associate Director, Lurie Cancer Center, Northwestern University Feinberg School of Medicine

  • (1993–2011) NorthShore University HealthSystem Board of Directors
  • (1995–1999) Director, Swedish Covenant Hospital Cancer Center

  • (1998–2011) Louise W. Coon Chair in Medicine and Director, Kellogg Cancer Care Centers, NorthShore University HealthSystem

  • (2009–Present) Clinical Professor, University of Chicago Pritzker School of Medicine

  • (July 2011–Present) Director for the Center for Molecular Medicine, NorthShore University HealthSystem

  • (2011–Present) Board of Directors, NorthShore University HealthSystem

  • (2003–2008) Deputy Editor, Archives of Internal Medicine

Honors and Awards

  • Gold Medal for standing First in the College for Bachelor of Science Degrees

  • Gold Medals for standing First in the University; Honors in Physiology, Pharmacology and Medicine in Medical School

  • 1983 - Certificate of Merit as Principal Investigator for Community Clinical Oncology Program, National Cancer Institute

  • 1991 - Who's Who in Medicine

  • 1995 - Who's Who in Science and Technology

  • 1997 - Who's Who in America

  • 1998-2013 - Best Doctors in America

  • 1999, 2001, 2003 - Listed How to Find Best Doctors, Chicago-metro region

  • 1997 - Illinois Laureate, American College of Physicians

  • 1997 - Distinguished Physician Award, India Medical Association

  • 1997 - Lecturer – 19th Annual Conference of Association of Radiation Oncologists of India

  • 2002 - Stephen A Weisman, M.D. Humanitarian Award, Cancer Wellness Center

  • 2003 - NorthShore University HealthSystem (NorthShore) Board of Directors Award for Program Development\

  • 2004 - Dean D.N.S. Chowdhari - Memorial Oration

  • 2009 - NorthShore University HealthSystem Physician Philanthropy Champions’ (PPC) Inaugural Award, Board of Directors

  • 2012 - Endeavor Health Medical Group Distinguished Physician Award

  • 2013 - Myra Rubenstein Weis Health Resource Center Award

  • 2013 - Plenary Session Lecture – Indian Academy of Neurology


Professional Memberships/Affiliations/Activities

  • 1977–1981 - Board of Directors, American Cancer Society, Chicago North Shore Division

  • 1978–1982 - Board of Directors, Hospice of North Shore

  • 1978– Scientific Program Committee, Association of Clini­cal Scientists

  • 1980 –1991 - Consultant, Medical Oncologist to Illinois Cancer Council

  • 1980–1989 - Member, Lung Cancer Study Group

  • 1981– NIH Ad Hoc Committee on Natl. Prostate Cancer Program

  • 1981– NIH Ad Hoc Study Sections on Translational Clinical Research

  • 1981– Member, NIH Team for Audit of Clinical Trials: Yale University, Roswell Park Memorial Institute, Mayo Clinic, etcetera

  • 1981–1985 - GU/GYN Steering Committee, ECOG, Co-Chairman

  • 1981–1985 - ECOG; P.I. Constitution, GU, Human Genetics, Nominating, and Institutional Review Committees

  • 1982–1987 - Co-Chairman, ECOG Forms Committee

  • 1982–1985 - Member, ECOG Cancer Control Steering Committee

  • 1986– Member, ECOG New Agents Committee

  • 1987– Member, ECOG Surgery Review Committee

  • 1991–1998 - Member, Executive Committee ECOG

  • 1991–1994 - Member, Exhibits Committee of ASCO

  • 1991–2000 - Gilda’s Club

  • 1994–1997 - Member, CansurFACS Advisory Committee, American College of Surgeons

  • 1996–2000 - Medical Advisory Board, Vida Health Care

  • 2004–2009 - Association of Professors of Medicine – Diversity Committee

  • 2014–Present -  Associate Editor of J. Surgical Oncology

Scholarly Work

Publications: Peer-Reviewed (115 full length papers and over 60 book chapters and proceedings of Symposia)

  1. Coleman O, Manola J, Hudes G, Khandekar JD,  Phase II evaluation of menogaril in advanced prostate cancer: An eastern cooperative oncology group study PA885. Amer. J Clin Oncol. Cancer Clinical Trials.  24: 150-54: 2001.

  2. Sener S, Milus S, Khandekar JD, - The spectrum of vascular lesions in the mammary skin, including breast angiosarcoma, following breast conservation treatment for breast cancer. J Amer Coll Surg. 193:22-28: 2001.

  3. Badi L, Khandekar J. Breast Cancer Survivors: The Primary Care Physician’s Role in Follow-up. Consultant. 1559: Nov. 2002.

  4. Badi L, Khandekar J. Colorectal Cancer Survivors: The Primary Care Physician’s Role in Follow-up. Consultant. 259: Feb. 2003.

  5. Chlebowski R, Hendrix SL, Langer RD, Stefanick M, Gass M, Lane D, Rodabough R, Gilligan MA, Cyr M, Thomson C, Khandekar JD, Influence of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women: the Women’s Health Initiative Randomized Trial. JAMA 2003; 289: 3243-3253.

  6. Rosenberg C, Greenland P, Khandekar J,  Association of Nonmelanoma Skin Cancer with Second Malignancy: The Women’s Health Initiative Observational Study. Cancer.100: 130-138: 2004.

  7. Rosenberg C, Khandekar J, Greeland, P, etal. Cutaneous Melanoma in Postmenopausal Women After Nonmelanoma Skin Carcinoma.  Cancer 106: 654-663, 2006.

  8. Anderson GL, Chlebowski RT, Rossouw JE, Rodabough RJ, McTiernan A, Margolis KL, Aggerwal A, Curb JD, Hendrix SL, Hubbell FA, Khandekar JD,  Prior hormone therapy and breast cancer risk in the Women’s Health Initiative randomized trial of estrogen plus progestin. Maturitas 55 103-115, 2006.

  9. Khandekar J, Khandekar M. Phase I clinical trials: Not just for safety anymore?.Archives of Internal Medicine 166:1440-1441. 2006.

  10. Carneiro BA, Brand RE, Fine E, Knop RH, Khandekar JD, etal. Phase I Trial of Fixed Dose Rate Infusion Gemcitabine with Gefitinib in Patients with Pancreatic Carcinoma.  Cancer Investigation. 25:366-371. 2007.

  11. Prentice RL, Thomson CA, Caan B, Hubbell FA, Anderson GL, Beresford SAA, Pettinger M, Lane DS, Lessin L, Yasmeen S, Singh B, Khandekar JD, Low-Fat Dietary Pattern and Cancer Incidence in the Women’s Health Initiative Dietary Modification Trial. J of National Cancer Institute.  99:1534-1542. 2007.

  12. Chlebowski R, Johnson K, Kooperberg C, Pettinger M, Wactawski-Wende J, Rohan T, Rossouw J, Lane D, O’Sullivan M, Yasmeen S, Hiatt R, Shikany J, Vitolins M, Khandekar J, Calcium plus Vitamin D Supplementation and the Risk of Breast Cancer. JNCI. 100(22): 1581-1591. 2008.

  13. Kabat GC, Kim M, Chlebowski RT, Khandekar J, A longitudinal study of the metabolic syndrome and risk of postmenapausal breast cancer. Cancer Epidemiol Biomarkers Prev. 2009 Jul; 18(7):2046-53. 2009.

  14. Dimri R, Bommi P, Sahasrabuddhe A, Khandekar J, Dimri G. Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.  Carcinogenesis. 31: 480-495.2009.

  15. Bomni P, Khandekar J, Dimri G. The polycomp group protein BMI is a target of HDAC inhibitors. Cell Cycle. 9:2663-73.2010.

  16. Chlebowski R, Johnson K, Lane D, Pettinger M, Kooperberg C, Wactawski-Wende J,  Rohan T, O’Sullivan M, Yasmeen S, Hiatt R,  Shikany J, Vitolins M, Khandekar J, 25-Hydroxyvitamin D Concentration, Vitamin D Intake and Joint Symptoms in Postmenopausal Women. Maturitas.68:73-78. 2011.

  17. Persell S, Kaiser D, Dolan N, Andrews B, Levi S, Khandekar J, Changes in Performance After Implementation of a Multifaceted Electronic-Health-Record-Based  Quality Improvement System. The UPQUAL Study. Medical Care. 49(2):117-125.  Feb. 2011.

  18. Simon M, Rosenberg C, Rodabough R, Greenland P, Ockene I, Roy H, Lane D, Cauley J, Khandekar J. Prospective Analysis of Association between Use of Statins or Other Lipid Lowering Agents and Colorectal Cancer Risk. Annals of Epidemiology 2012; 22:17-27.

  19. Brockstein B, Hensing T, Carro G, Obel J, Khandekar J, The Effect of an Electronic Health Record on the Culture of an Outpatient Medical Oncology Practice in a 4-hospital Integrated Healthcare System: 5 Year Experience. Journal of Oncology Practice. 2011; 7:e20-e24.

  20. Japtag, D., Rosenberg, C.A., Martin, L.W., Pettinger, M., Khandekar, J., Lane, D., Ockene, I. and Simon, M.S. (2012), Prospective analysis of association between use of statins and melanoma risk in the Women’s Health Initiative. Cancer: 2012:118:5124-5131.

  21. Roy, H., Khandekar, J.D., (2012) APC Gene Testing for Familial Adenomatosis Polysposis. JAMA 2012; 308: 514-515.

  22. Stephen D. Persell, MD, MPH; Janardan Khandekar, MD; Thomas Gavagan, MD; Nancy C. Dolan, MD; Sue Levi, RN, MBA; Darren Kaiser, MS; Elisha M. Friesema, BA, CCRP; Ji Young Lee, MS; and David W. Baker, MD, MPH - Implementation of EHR-Based Strategies to Improve Outpatient CAD Care.  Am Journal Managed Care. 2012;18(10):603-610).

  23. Rodaboh, R., Khandekar,JD., Simon, M.  Breast Cancer in Postmenopausal Women after Non-melanomatous Skin Cancer:  The Women’s Health Initiative Observational study. Breast Cancer Research Treatment (2013) 139:821-831. 

  24. Gulukota, K, Helseth,Jr, DL and Khandekar, JD – Direct observation of genomic heterogeneity through local haplotyping analysis.  BMC Genomics 2014, 15:418 doi:10.1186/1471-2164-15-418.


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