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Frequently Asked Questions

What are pharmacogenomics and MedClueRx?

Pharmacogenomics is the study of how our genetic makeup influences our response to different medications. The focus is on providing safe and effective medications. MedClueRx is NorthShore's pharmacogenomics program, which utilizes our proprietary MedClueRx kit, testing and analysis, and integrates your results into your medical record to support your physicians' informed decisions about future medications.

Who should get MedClueRx?

Pharmacogenomics testing is particularly valuable before you have tried several medications for a condition. We know that 98% of patients who take the MedClueRx test have at least one result that may impact their care. It is also useful if you feel your medications are not working or have experienced adverse side effects.

How do I get the MedClueRx kit?

Contact your NorthShore primary care physician via a NorthShoreConnect message or schedule an appointment with your physician to discuss the MedClueRx program. Your primary care physician can initiate the process. If you do not have a NorthShore primary care physician, call 847.570.GENE (4363).

Which drugs are included in the test panel?

Every day the evolving field of pharmacogenomics yields novel information about drug-gene pairs. The list of drugs found to be most affected by genotype, or genetic makeup, changes with each new discovery. Some common medications (organized by condition) include:

  • Cardiovascular Conditions
    clopidogrel (Plavix®)
    warfarin (Coumadin®)
    simvastatin (Zocor®)

  • Depression
    citalopram (Celexa®)
    paroxetine (Paxil®)
    fluoxetine (Prozac®)

  • Epilepsy
    phenytoin (Dilantin®)

  • Gastrointestinal Disorders
    mercaptopurine (Purinethol®)
    azathioprine (Imuran®)

  • Infectious Diseases
    voriconazole (Vfend®)

  • Pain Management
    codeine (Tylenol #3®)
    tramadol (Ultram)

What type of sample is needed?

A simple cheek swab using our in-home kit is all that is required.

How much does MedClueRx cost?

The cost of the pharmacogenomics test is $450. For NorthShoreConnect members, we are pleased to offer this testing program at a cost of $225. 

Is MedClueRx covered by insurance?

Pharmacogenomics testing may be a covered benefit of insurance plans depending on your diagnosis and insurance. NorthShore can provide an itemized bill for submission to insurance, Flexible Spending Account (FSA) or Health Savings Account (HSA). Call 847.570.5000.

What happens to my DNA once the test is complete?

Your privacy is assured. Samples and genetic information are stored securely in accordance with HIPAA and other governmental regulations. Any remaining DNA is destroyed.

How and when will I receive my test results?

Test results will be reviewed by NorthShore's pharmacogenomics specialists and available to your NorthShore primary care physician 2-3 weeks after your sample is received. A copy of the report will also be mailed to you.

How are my results used by my physician in my ongoing care?

Your results become a part of your electronic medical record. Your NorthShore physician(s) are alerted if you have a pharmacogenomic result and can use this information to inform decisions about future medications.