Dr. Ashvini P. Premkumar | NorthShore
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Ashvini P. Premkumar, M.D.

Ashvini P. Premkumar, M.D.

Ashvini P. Premkumar, M.D.

  • Locations
    Locations
    A

    NorthShore Medical Group

    2180 Pfingsten Rd.
    Suite 2000
    Glenview, IL 60026
    847.570.2570 847.657.5708 fax Get Directions This location is wheelchair accessible.
    B

    NorthShore Medical Group

    1000 Central St.
    Suite 880
    Evanston, IL 60201
    847.570.2570 847.657.5708 fax Get Directions This location is wheelchair accessible.
  • Publications
    Publications
    • Tremor: etiology, phenomenology, and clinical features.

      Disease-a-month : DM 2011 Mar

      Authors: Evidente VG, Premkumar AP, Adler CH, Caviness JN, Driver-Dunckley E, Lyons MK
      Abstract
      To compare the medication dose reduction between deep brain stimulation (DBS) of the globus pallidus interna (GPi) vs subthalamic nucleus (STN) in matched patients with Parkinson's disease (PD).
      Records of 12 patients with PD who underwent GPi-DBS at our institution from 2002 to 2008 were matched by pre-operative PD medication doses and pre-operative motor Unified Parkinson's Disease Rating Scale (UPDRS) scores to 12 cases of STN-DBS. PD medication doses were converted to levodopa equivalent doses (LEDs).
      GPi and STN groups had similar mean pre-operative LEDs and motor UPDRS scores. At 6 months post-DBS, there was no significant difference in percent reduction in LEDs between the GPi (47.95%) and STN (37.47%) groups (P = 0.52). The mean post-operative 'medication off/stimulation on' motor UPDRS scores did not differ significantly between GPi (15.33) and STN (16.25) groups (P = 0.74). The mean percent reduction in motor UPDRS scores was also similar between GPi (58.44%) and STN (58.98%) patients (P = 0.94).
      We conclude that in disease-matched patients with PD undergoing DBS, both GPi and STN may result in similar reduction in PD medication doses.
      PMID: 21447420 [PubMed - as supplied by publisher]
    • Olfaction in the elderly: a cross-sectional analysis comparing Parkinson's disease with controls and other disorders.

      The International journal of neuroscience 2010 Jan

      Authors: McKinnon J, Evidente V, Driver-Dunckley E, Premkumar A, Hentz J, Shill H, Sabbagh M, Caviness J, Connor D, Adler C
      Abstract
      Olfactory dysfunction in Parkinson's disease (PD) is an association that has been well documented in the medical literature, although the underlying pathophysiologic mechanism has not been clearly elucidated. In the Sun Health Research Institute Brain and Body Donation Program, subjects were tested for olfactory function. Olfaction was impaired in subjects with clinically probable PD but not those with essential tremor (ET), restless legs syndrome (RLS), or mild cognitive impairment. In the elderly control population there were no differences between genders and the UPSIT score decreased by 3.2 points per decade. These data confirm previous findings in PD, ET, and RLS, and expand the data for an elderly control population.
      PMID: 20128670 [PubMed - as supplied by publisher]
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