EH13-132: Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) – Project II: Validation Study
Aims: The purpose of this study is to learn more about symptoms of pelvic pain. The study involves a 30-min online questionnaire.
Diagnoses: Interstitial Cystitis (bladder pain), Chronic Prostatitis, Irritable Bowel Syndrome, Fibromyalgia, Chronic Fatigue Syndrome or Healthy Controls
Principal Investigator: Frank Tu, MD, MPH
IRB Approval Number: EH13-132
Sponsor:  NIH/NIDDK/Northwestern University
Contact:  Interested patients should contact Julia Kane at 847.570.2622. Only participants who have undergone medical care through NorthShore University HealthSystem and whose diagnoses can be verified are eligible.
Open to Enrollment:  Yes

Autonomic Biomarkers of Chronic Pain Pathology
Aims: The purpose of this study is to investigate neurochemicals in urine. Researchers want to see if the autonomic nervous system (the portion that regulates heart rate and breathing) is responsible for increased pain in multiple chronic pelvic pain conditions. The study involves the collection of 2 urine samples.
Diagnoses: Dysmenorrhea (painful periods), Vulvodynia (chronic vulvar pain), Interstitial Cystitis (bladder pain), or Healthy Controls
Principal Investigator: Kevin Hellman, PhD
IRB Approval Number: EH11-112
Sponsor: NorthShore University HealthSystem
Contact: Interested participants should contact Julia Kane at 847.570.2622. Only participants whose diagnoses can be verified are eligible.
Open to Enrollment: Yes

Novel Approaches to Investigation of Menstrual Pain
Aims: The purpose of this study is to find out how contractions of the uterus cause menstrual pain. Specifically, we want to find out if women with more pain have more electrical and muscle activity than healthy controls. We will also see how the nervous system responds (heart and respiratory rate). The study involves one 4-hour session during the participant’s menstrual period.
Diagnosis: Dysmenorrhea (painful periods)
Principal Investigator: Kevin Hellman, PhD
IRB Approval Number: EH11-210
Sponsor: NorthShore University HealthSystem  
Contact: Interested participants should contact Julia Kane at 847.570.2622
Open to Enrollment: Yes

Vasopressin Administration During Laparoscopic Myomectomy: A Randomized Controlled Trial
Aims: The main purpose of this study is to compare blood loss at the time of laparoscopic or robotically-assisted laparoscopic myomectomy when using different amounts of dilute vasopressin solution.  A myomectomy is a surgical procedure to remove fibroids from the uterus and vasopressin is a synthetic drug used to help decrease blood loss at the time of gynecologic surgery.
Diagnosis: Patients undergoing laparoscopic myomectomy (fibroid surgery) through NorthShore University Healthy System.
Principal Investigator: Sangeeta Senapati, MD
IRB Approval Number: EH11-113
Sponsor: NorthShore University HealthSystem  
Contact: Interested participants should contact Emily Borushko at 847.570.2686. Only participants who are candidates for laparoscopic or robotically-assisted laparoscopic myomectomy at NorthShore University HealthSystem are eligible.
Open to Enrollment:  Yes

A Randomized Double-Blind, Placebo Controlled Study to Evaluate the Safety and Efficacy of Elagolix in Subjects with Moderate to Severe Endometriosis-Associated Pain
Aims:
 The purpose of this study is to test a drug called Elagolix for treating women with endometriosis-associated pain.  Participation lasts approximately 1-2 years and involves monthly study visits to Evanston Hospital along with the use of a daily electronic diary to collect data from home about endometriosis symptoms. Participants are asked to take study capsules (which may contain Elagolix or placebo) for 6 months.
Diagnosis:
Endometriosis
Principal Investigator:
Frank Tu, MD, MPH
IRB Approval Number:
EH13-220
Sponsor:
  AbbVie
Contact:
  Interested participants should contact Julia Kane at 847.570.2622. Only participants whose diagnosis of endometriosis has been verified by surgery (laparoscopy or laparotomy) are eligible.
Open to Enrollment:
  Yes

× Alternate Text