Ioannis Koktzoglou , PhD

• Ph.D. in Biomedical Engineering, Northwestern University, Evanston, IL
• M.S. in Biomedical Engineering, Northwestern University, Evanston, IL
• B.S. in Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL

Our laboratory develops and validates next-generation magnetic resonance imaging (MRI) technologies for diagnosing human disease. Our work ranges from the conception and development of altogether new MRI acquisition, reconstruction and image analysis methods, to the validation of these innovative technologies through research studies. The ultimate aim of our research is to translate new technologies from the “bench to the bedside” to improve patient care.

Recent efforts have included the development of quantitative and highly sensitive methods for imaging of cerebrovascular disease and cancer, as well as the development and use of machine learning methods to shorten scan times, improve image quality, enrich diagnostic information, and boost diagnostic accuracy.

Ioannis Koktzoglou, PhD is a Research Scientist at NorthShore University HealthSystem Research Institute and a Senior Clinician Researcher at the University of Chicago Pritzker School of Medicine.  He completed his undergraduate studies at the University of Illinois at Urbana-Champaign and his graduate studies at Northwestern University.  Dr. Koktzoglou is an internationally-recognized expert in magnetic resonance imaging (MRI) and has developed many MRI technologies for improved imaging of cardiovascular disease and cancer.  He has served as principal investigator and co-investigator on research projects supported by the National Institutes of Health and American Heart Association, authored or co-authored over 80 peer-reviewed scientific manuscripts in leading international journals, delivered or contributed to over 180 presentations at international scientific meetings, served as peer-reviewer for 20 scientific journals, and holds 17 patents.

• Distinguished Reviewer, Magnetic Resonance in Medicine, 2011, 2014-2015, 2017-2019
• Distinguished Reviewer, Journal of Magnetic Resonance Imaging, 2012-2013, 2015, 2017-2018
• Early Career Reviewer Program, National Institutes of Health, 2015
• Pohost Best Paper Award Finalist, Journal of Cardiovascular Magnetic Resonance, 2008
• Dr. John N. Nicholson Fellowship, The Graduate School, Northwestern University, 2003-2006

• Member, International Society for Magnetic Resonance in Medicine
• Member, Society for Cardiovascular Magnetic Resonance

Peer-Reviewed Journal Publications:

1. Koktzoglou I, Huang R, Edelman RR. Quantitative time-of-flight MR angiography for simultaneous luminal and hemodynamic evaluation of the intracranial arteries. Magn Reson Med. 2022 Jan;87(1):150-162. doi: 10.1002/mrm.28969. Epub 2021 Aug 10.
2. Decker JA, Fischer AM, Schoepf UJ, Xiong F, Todoran TM, Aldinger J, Ellis L, Edelman RR, Koktzoglou I, Emrich T, Varga-Szemes A. Quiescent-Interval Slice-Selective MRA Accurately Estimates Intravascular Stent Dimensions Prior to Intervention in Patients With Peripheral Artery Disease. J Magn Reson Imaging. 2022 Jan;55(1):246-254. doi: 10.1002/jmri.27864. Epub 2021 Jul 29.
3. Edelman RR, Leloudas N, Pang J, Koktzoglou I. Dark blood cardiovascular magnetic resonance of the heart, great vessels, and lungs using electrocardiographic-gated three-dimensional unbalanced steady-state free precession. J Cardiovasc Magn Reson. 2021 Nov 1;23(1):127. doi: 10.1186/s12968-021-00808-2.
4. Varga-Szemes A, Aouad P, Schoepf UJ, Emrich T, Yacoub B, Todoran TM, Koktzoglou I, Edelman RR. Comparison of 2D and 3D quiescent-interval slice-selective non-contrast MR angiography in patients with peripheral artery disease. MAGMA. 2021 Oct;34(5):649-658. doi: 10.1007/s10334-021-00927-y. Epub 2021 May 8.
5. Navot B, Hecht EM, Lim RP, Edelman RR, Koktzoglou I. MR Angiography Series: Fundamentals of Non-Contrast-enhanced MR Angiography. Radiographics. 2021 Sep-Oct;41(5):E157-E158. doi: 10.1148/rg.2021210141.
6. Koktzoglou I, Huang R, Ankenbrandt WJ, Walker MT, Edelman RR. Super-resolution head and neck MRA using deep machine learning. Magn Reson Med. 2021 Jul;86(1):335-345. doi: 10.1002/mrm.28738. Epub 2021 Feb 22.
7. Edy E, Rankin AJ, Lees JS, Barrientos PH, Woodward R, Stoumpos S, Koktzoglou I, Edelman RR, Radjenovic A, Mark PB, Roditi GH. Cardiovascular magnetic resonance for the detection of descending thoracic aorta calcification in patients with end-stage renal disease. J Cardiovasc Magn Reson. 2021 Jun 24;23(1):85. doi: 10.1186/s12968-021-00769-6.
8. Salehi Ravesh M, Lebenatus A, Bonietzki A, Hensler J, Koktzoglou I, Edelman RR, Graessner J, Jansen O, Both M. High-resolution, non-contrast-enhanced magnetic resonance angiography of the wrist, hand and digital arteries using optimized implementation of Cartesian quiescent interval slice selective (QISS) at 1.5 T. Magn Reson Imaging. 2021 May;78:58-68. doi: 10.1016/j.mri.2021.02.008. Epub 2021 Feb 11.
9. Varga-Szemes A, Penmetsa M, Emrich T, Todoran TM, Suranyi P, Fuller SR, Edelman RR, Koktzoglou I, Schoepf UJ. Diagnostic accuracy of non-contrast quiescent-interval slice-selective (QISS) MRA combined with MRI-based vascular calcification visualization for the assessment of arterial stenosis in patients with lower extremity peripheral artery disease. Eur Radiol. 2021 May;31(5):2778-2787. doi: 10.1007/s00330-020-07386-4. Epub 2020 Oct 17.
10. Edelman RR, Koktzoglou I. "Push-button" noncontrast MR angiography using balanced T(1) relaxation-enhanced steady-state (bT1RESS). Magn Reson Med. 2021 Mar;85(3):1248-1257. doi: 10.1002/mrm.28492. Epub 2020 Sep 16.
11. Koktzoglou I, Huang R, Ong AL, Aouad PJ, Walker MT, Edelman RR. High spatial resolution whole-neck MR angiography using thin-slab stack-of-stars quiescent interval slice-selective acquisition. Magn Reson Med. 2020 Dec;84(6):3316-3324. doi: 10.1002/mrm.28339. Epub 2020 Jun 10.
12. Aouad P, Koktzoglou I, Milani B, Serhal A, Nazari J, Edelman RR. Radial-based acquisition strategies for pre-procedural non-contrast cardiovascular magnetic resonance angiography of the pulmonary veins. J Cardiovasc Magn Reson. 2020 Nov 30;22(1):78. doi: 10.1186/s12968-020-00685-1.
13. Salehi Ravesh M, Tesch K, Lebenatus A, Koktzoglou I, Edelman RR, Eden M, Langguth P, Graessner J, Jansen O, Both M. Clinical Value of Noncontrast-Enhanced Radial Quiescent-Interval Slice-Selective (QISS) Magnetic Resonance Angiography for the Diagnosis of Acute Pulmonary Embolism Compared to Contrast-Enhanced Computed Tomography and Cartesian Balanced Steady-State Free Precession. J Magn Reson Imaging. 2020 Nov;52(5):1510-1524. doi: 10.1002/jmri.27240. Epub 2020 Jun 14.
14. Edelman R, Leloudas N, Pang J, Bailes J, Merrell R, Koktzoglou I. Twofold improved tumor-to-brain contrast using a novel T1 relaxation-enhanced steady-state (T(1)RESS) MRI technique. Sci Adv. 2020 Oct 28;6(44):eabd1635. doi: 10.1126/sciadv.abd1635. Print 2020 Oct.
15. Koktzoglou I, Huang R, Ong AL, Aouad PJ, Aherne EA, Edelman RR. Feasibility of a sub-3-minute imaging strategy for ungated quiescent interval slice-selective MRA of the extracranial carotid arteries using radial k-space sampling and deep learning-based image processing. Magn Reson Med. 2020 Aug;84(2):825-837. doi: 10.1002/mrm.28179. Epub 2020 Jan 23.
16. Edelman RR, Aherne E, Leloudas N, Pang J, Koktzoglou I. Near-isotropic noncontrast MRA of the renal and peripheral arteries using a thin-slab stack-of-stars quiescent interval slice-selective acquisition. Magn Reson Med. 2020 May;83(5):1711-1720. doi: 10.1002/mrm.28032. Epub 2019 Oct 21.
17. Bastiaansen JAM, Piccini D, Di Sopra L, Roy CW, Heerfordt J, Edelman RR, Koktzoglou I, Yerly J, Stuber M. Natively fat-suppressed 5D whole-heart MRI with a radial free-running fast-interrupted steady-state (FISS) sequence at 1.5T and 3T. Magn Reson Med. 2020 Jan;83(1):45-55. doi: 10.1002/mrm.27942. Epub 2019 Aug 27.
18. Varga-Szemes A, Aherne EA, Schoepf UJ, Todoran TM, Koktzoglou I, Edelman RR. Free-Breathing Fast Low-Angle Shot Quiescent-Interval Slice-Selective Magnetic Resonance Angiography for Improved Detection of Vascular Stenoses in the Pelvis and Abdomen: Technical Development. Invest Radiol. 2019 Dec;54(12):752-756. doi: 10.1097/RLI.0000000000000592.
19. Koktzoglou I, Aherne EA, Walker MT, Meyer JR, Edelman RR. Ungated nonenhanced radial quiescent interval slice-selective (QISS) magnetic resonance angiography of the neck: Evaluation of image quality. J Magn Reson Imaging. 2019 Dec;50(6):1798-1807. doi: 10.1002/jmri.26781. Epub 2019 May 11.
20. Aherne EA, Koktzoglou I, Lind BB, Edelman RR. Dynamic quantitative nonenhanced magnetic resonance angiography of the abdominal aorta and lower extremities using cine fast interrupted steady-state in combination with arterial spin labeling: a feasibility study. J Cardiovasc Magn Reson. 2019 Sep 2;21(1):55. doi: 10.1186/s12968-019-0562-3.
21. Peters S, Huhndorf M, Jensen-Kondering U, Larsen N, Koktzoglou I, Edelman RR, Graessner J, Both M, Jansen O, Salehi Ravesh M. Non-Contrast-Enhanced Carotid MRA: Clinical Evaluation of a Novel Ungated Radial Quiescent-Interval Slice-Selective MRA at 1.5T. AJNR Am J Neuroradiol. 2019 Sep;40(9):1529-1537. doi: 10.3174/ajnr.A6171. Epub 2019 Aug 8.
22. Salehi Ravesh M, Langguth P, Pfarr JA, Schupp J, Trentmann J, Koktzoglou I, Edelman RR, Graessner J, Greiser A, Hautemann D, Hennemuth A, Both M, Jansen O, Hövener JB, Schäfer JP. Non-contrast-enhanced magnetic resonance imaging for visualization and quantification of endovascular aortic prosthesis, their endoleaks and aneurysm sacs at 1.5 T. Magn Reson Imaging. 2019 Jul;60:164-172. doi: 10.1016/j.mri.2019.05.012. Epub 2019 May 7.
23. Cavallo AU, Koktzoglou I, Edelman RR, Gilkeson R, Mihai G, Shin T, Rajagopalan S. Noncontrast Magnetic Resonance Angiography for the Diagnosis of Peripheral Vascular Disease. Circ Cardiovasc Imaging. 2019 May;12(5):e008844. doi: 10.1161/CIRCIMAGING.118.008844.
24. Serhal A, Koktzoglou I, Edelman RR. Feasibility of Image Fusion for Concurrent MRI Evaluation of Vessel Lumen and Vascular Calcifications in Peripheral Arterial Disease. AJR Am J Roentgenol. 2019 Apr;212(4):914-918. doi: 10.2214/AJR.18.20000. Epub 2019 Feb 4.
25. Edelman RR, Koktzoglou I. Noncontrast MR angiography: An update. J Magn Reson Imaging. 2019 Feb;49(2):355-373. doi: 10.1002/jmri.26288. Epub 2018 Dec 19.
26. Edelman RR, Carr M, Koktzoglou I. Advances in non-contrast quiescent-interval slice-selective (QISS) magnetic resonance angiography. Clin Radiol. 2019 Jan;74(1):29-36. doi: 10.1016/j.crad.2017.12.003. Epub 2018 Jan 12.
27. Shen D, Edelman RR, Robinson JD, Haji-Valizadeh H, Messina M, Giri S, Koktzoglou I, Rigsby CK, Kim D. Single-Shot Coronary Quiescent-Interval Slice-Selective Magnetic Resonance Angiography Using Compressed Sensing: A Feasibility Study in Patients With Congenital Heart Disease. J Comput Assist Tomogr. 2018 Sep-Oct;42(5):739-746. doi: 10.1097/RCT.0000000000000760.
28. Serhal A, Koktzoglou I, Aouad P, Carr JC, Giri S, Morcos O, Edelman RR. Cardiovascular magnetic resonance imaging of aorto-iliac and ilio-femoral vascular calcifications using proton density-weighted in-phase stack of stars. J Cardiovasc Magn Reson. 2018 Aug 6;20(1):51. doi: 10.1186/s12968-018-0479-2.
29. Koktzoglou I, Edelman RR. Radial fast interrupted steady-state (FISS) magnetic resonance imaging. Magn Reson Med. 2018 Apr;79(4):2077-2086. doi: 10.1002/mrm.26881. Epub 2017 Aug 30.
30. Edelman RR, Serhal A, Pursnani A, Pang J, Koktzoglou I. Cardiovascular cine imaging and flow evaluation using Fast Interrupted Steady-State (FISS) magnetic resonance. J Cardiovasc Magn Reson. 2018 Feb 19;20(1):12. doi: 10.1186/s12968-018-0433-3.
31. Koktzoglou I, Edelman RR. Super-resolution intracranial quiescent interval slice-selective magnetic resonance angiography. Magn Reson Med. 2018 Feb;79(2):683-691. doi: 10.1002/mrm.26715. Epub 2017 May 3.
32. Lim RP, Trajcevska E, Al Rawi F, Gooneratne D, Ang W, Perchyonok Y, Fitt G, Kemp A, Giri S, Piccini D, Brodtmann A, Dewey H, Koktzoglou I. Noncontrast Hybrid Arterial Spin-Labeled Imaging of the Intracranial Arteries. J Comput Assist Tomogr. 2017 Nov/Dec;41(6):854-860. doi: 10.1097/RCT.0000000000000633.
33. Edelman RR, Silvers RI, Thakrar KH, Metzl MD, Nazari J, Giri S, Koktzoglou I. Nonenhanced MR angiography of the pulmonary arteries using single-shot radial quiescent-interval slice-selective (QISS): a technical feasibility study. J Cardiovasc Magn Reson. 2017 Jun 30;19(1):48. doi: 10.1186/s12968-017-0365-3.
34. Ferreira Botelho MP, Koktzoglou I, Collins JD, Giri S, Carr JC, Gupta N, Edelman RR. MR imaging of iliofemoral peripheral vascular calcifications using proton density-weighted, in-phase three-dimensional stack-of-stars gradient echo. Magn Reson Med. 2017 Jun;77(6):2146-2152. doi: 10.1002/mrm.26295. Epub 2016 Jun 14.
35. Hodnett PA, Koktzoglou I, Davarpanah AH, Scanlon TG, Collins JD, Sheehan JJ, Dunkle EE, Gupta N, Carr JC, Edelman RR. Evaluation of Peripheral Arterial Disease with Nonenhanced Quiescent-Interval Single-Shot MR Angiography. Radiology. 2017 Feb;282(2):614. doi: 10.1148/radiol.2017164042.
36. Edelman RR, Botelho M, Pursnani A, Giri S, Koktzoglou I. Improved dark blood imaging of the heart using radial balanced steady-state free precession. J Cardiovasc Magn Reson. 2016 Oct 19;18(1):69. doi: 10.1186/s12968-016-0293-7.
37. Koktzoglou I, Murphy IG, Giri S, Edelman RR. Quiescent interval low angle shot magnetic resonance angiography of the extracranial carotid arteries. Magn Reson Med. 2016 May;75(5):2072-7. doi: 10.1002/mrm.25791. Epub 2015 Jun 15.
38. Koktzoglou I, Walker MT, Meyer JR, Murphy IG, Edelman RR. Nonenhanced hybridized arterial spin labeled magnetic resonance angiography of the extracranial carotid arteries using a fast low angle shot readout at 3 Tesla. J Cardiovasc Magn Reson. 2016 Apr 12;18:18. doi: 10.1186/s12968-016-0238-1.
39. Koktzoglou I, Giri S, Piccini D, Grodzki DM, Flanagan O, Murphy IG, Gupta N, Collins JD, Edelman RR. Arterial spin labeled carotid MR angiography: A phantom study examining the impact of technical and hemodynamic factors. Magn Reson Med. 2016 Jan;75(1):295-301. doi: 10.1002/mrm.25611. Epub 2015 Feb 13.
40. Edelman RR, Giri S, Pursnani A, Botelho MP, Li W, Koktzoglou I. Breath-hold imaging of the coronary arteries using Quiescent-Interval Slice-Selective (QISS) magnetic resonance angiography: pilot study at 1.5 Tesla and 3 Tesla. J Cardiovasc Magn Reson. 2015 Nov 23;17:101. doi: 10.1186/s12968-015-0205-2.
41. Lim RP, Koktzoglou I. Noncontrast magnetic resonance angiography: concepts and clinical applications. Radiol Clin North Am. 2015 May;53(3):457-76. doi: 10.1016/j.rcl.2014.12.003.
42. Edelman RR, Flanagan O, Grodzki D, Giri S, Gupta N, Koktzoglou I. Projection MR imaging of peripheral arterial calcifications. Magn Reson Med. 2015 May;73(5):1939-45. doi: 10.1002/mrm.25320. Epub 2014 Jun 24.
43. Koktzoglou I, Meyer JR, Ankenbrandt WJ, Giri S, Piccini D, Zenge MO, Flanagan O, Desai T, Gupta N, Edelman RR. Nonenhanced arterial spin labeled carotid MR angiography using three-dimensional radial balanced steady-state free precession imaging. J Magn Reson Imaging. 2015 Apr;41(4):1150-6. doi: 10.1002/jmri.24640. Epub 2014 Apr 16.
44. Edelman RR, Giri S, Murphy IG, Flanagan O, Speier P, Koktzoglou I. Ungated radial quiescent-inflow single-shot (UnQISS) magnetic resonance angiography using optimized azimuthal equidistant projections. Magn Reson Med. 2014 Dec;72(6):1522-9. doi: 10.1002/mrm.25477. Epub 2014 Sep 24.
45. Koktzoglou I, Mistretta CA, Giri S, Dunkle EE, Amin P, Edelman RR. Simultaneous static and cine nonenhanced MR angiography using radial sampling and highly constrained back projection reconstruction. Magn Reson Med. 2014 Oct;72(4):1079-86. doi: 10.1002/mrm.25008. Epub 2013 Nov 11.
46. Amin P, Collins JD, Koktzoglou I, Molvar C, Markl M, Edelman RR, Carr JC. Evaluating peripheral arterial disease with unenhanced quiescent-interval single-shot MR angiography at 3 T. AJR Am J Roentgenol. 2014 Apr;202(4):886-93. doi: 10.2214/AJR.13.11243.
47. Tan H, Koktzoglou I, Prasad PV. Renal perfusion imaging with two-dimensional navigator gated arterial spin labeling. Magn Reson Med. 2014 Feb;71(2):570-9. doi: 10.1002/mrm.24692.
48. Edelman RR, Giri S, Dunkle E, Galizia M, Amin P, Koktzoglou I. Quiescent-inflow single-shot magnetic resonance angiography using a highly undersampled radial k-space trajectory. Magn Reson Med. 2013 Dec;70(6):1662-8. doi: 10.1002/mrm.24596. Epub 2013 Jan 24.
49. Koktzoglou I. Gray blood magnetic resonance for carotid wall imaging and visualization of deep-seated and superficial vascular calcifications. Magn Reson Med. 2013 Jul;70(1):75-85. doi: 10.1002/mrm.24445. Epub 2012 Aug 8.
50. Koktzoglou I. 4D Dark blood arterial wall magnetic resonance imaging: methodology and demonstration in the carotid arteries. Magn Reson Med. 2013 Apr;69(4):956-65. doi: 10.1002/mrm.24647. Epub 2013 Feb 11.
51. Offerman EJ, Koktzoglou I, Glielmi C, Sen A, Edelman RR. Prospective self-gated nonenhanced magnetic resonance angiography of the peripheral arteries. Magn Reson Med. 2013 Jan;69(1):158-62. doi: 10.1002/mrm.24240. Epub 2012 Mar 5.
52. Mordini FE, Koktzoglou I, Edelman RR. Time-resolved spin-labeled balanced steady-state free precession cineangiography for visualizing intracardiac shunt: technical considerations and clinical feasibility. Magn Reson Med. 2012 Dec;68(6):1798-806. doi: 10.1002/mrm.24191. Epub 2012 Mar 27.
53. Tan H, Koktzoglou I, Glielmi C, Galizia M, Edelman RR. Optimization of single shot 3D breath-hold non-enhanced MR angiography of the renal arteries. J Cardiovasc Magn Reson. 2012 May 19;14(1):30. doi: 10.1186/1532-429X-14-30.
54. Hodnett PA, Ward EV, Davarpanah AH, Scanlon TG, Collins JD, Glielmi CB, Bi X, Koktzoglou I, Gupta N, Carr JC, Edelman RR. Peripheral arterial disease in a symptomatic diabetic population: prospective comparison of rapid unenhanced MR angiography (MRA) with contrast-enhanced MRA. AJR Am J Roentgenol. 2011 Dec;197(6):1466-73. doi: 10.2214/AJR.10.6091.
55. Koktzoglou I, Gupta N, Edelman RR. Nonenhanced extracranial carotid MR angiography using arterial spin labeling: improved performance with pseudocontinuous tagging. J Magn Reson Imaging. 2011 Aug;34(2):384-94. doi: 10.1002/jmri.22628.
56. Hodnett PA, Koktzoglou I, Davarpanah AH, Scanlon TG, Collins JD, Sheehan JJ, Dunkle EE, Gupta N, Carr JC, Edelman RR. Evaluation of peripheral arterial disease with nonenhanced quiescent-interval single-shot MR angiography. Radiology. 2011 Jul;260(1):282-93. doi: 10.1148/radiol.11101336. Epub 2011 Apr 18.
57. Offerman EJ, Hodnett PA, Edelman RR, Koktzoglou I. Nonenhanced methods for lower-extremity MRA: a phantom study examining the effects of stenosis and pathologic flow waveforms at 1.5T. J Magn Reson Imaging. 2011 Feb;33(2):401-8. doi: 10.1002/jmri.22457.
58. Koktzoglou I, Sheehan JJ, Dunkle EE, Breuer FA, Edelman RR. Highly accelerated contrast-enhanced MR angiography: improved reconstruction accuracy and reduced noise amplification with complex subtraction. Magn Reson Med. 2010 Dec;64(6):1843-8. doi: 10.1002/mrm.22567.
59. Haque M, Koktzoglou I, Li W, Carbray J, Prasad P. Functional MRI of liver using BOLD MRI: effect of glucose. J Magn Reson Imaging. 2010 Oct;32(4):988-91. doi: 10.1002/jmri.22329.
60. McCommis KS, Koktzoglou I, Zhang H, Goldstein TA, Northrup BE, Li D, Gropler RJ, Zheng J. Improvement of hyperemic myocardial oxygen extraction fraction estimation by a diffusion-prepared sequence. Magn Reson Med. 2010 Jun;63(6):1675-82. doi: 10.1002/mrm.22427.
61. Wu Y, Ragin AB, Du H, Sidharthan S, Dunkle EE, Koktzoglou I, Edelman RR. Sub-millimeter isotropic MRI for segmentation of subcortical brain regions and brain visualization. J Magn Reson Imaging. 2010 Apr;31(4):980-6. doi: 10.1002/jmri.22120.
62. Edelman RR, Sheehan JJ, Dunkle E, Schindler N, Carr J, Koktzoglou I. Quiescent-interval single-shot unenhanced magnetic resonance angiography of peripheral vascular disease: Technical considerations and clinical feasibility. Magn Reson Med. 2010 Apr;63(4):951-8. doi: 10.1002/mrm.22287.
63. Tsaftaris SA, Offerman E, Edelman RR, Koktzoglou I. Fully automated reconstruction of ungated ghost magnetic resonance angiograms. J Magn Reson Imaging. 2010 Mar;31(3):655-62. doi: 10.1002/jmri.22092.
64. Dharmakumar R, Zhang Z, Koktzoglou I, Tsaftaris SA, Li D. Dual-contrast cellular magnetic resonance imaging. Mol Imaging. 2009 Sep-Oct;8(5):254-63.
65. Edelman RR, Koktzoglou I, Ankenbrandt WJ, Dunkle EE. Cerebral venography using fluid-suppressed STARFIRE. Magn Reson Med. 2009 Aug;62(2):538-43. doi: 10.1002/mrm.22026.
66. Koktzoglou I, Edelman RR. Ghost magnetic resonance angiography. Magn Reson Med. 2009 Jun;61(6):1515-9. doi: 10.1002/mrm.21943.
67. Koktzoglou I, Edelman RR. STAR and STARFIRE for flow-dependent and flow-independent noncontrast carotid angiography. Magn Reson Med. 2009 Jan;61(1):117-24. doi: 10.1002/mrm.21769.
68. Edelman RR, Koktzoglou I. Unenhanced flow-independent MR venography by using signal targeting alternative radiofrequency and flow-independent relaxation enhancement. Radiology. 2009 Jan;250(1):236-45. doi: 10.1148/radiol.2493080496.
69. Edelman RR, Dunkle E, Koktzoglou I, Griffin A, Russell EJ, Ankenbrandt W, Ragin A, Carrillo A. Rapid whole-brain magnetic resonance imaging with isotropic resolution at 3 Tesla. Invest Radiol. 2009 Jan;44(1):54-9. doi: 10.1097/RLI.0b013e31818eee3c.
70. Koktzoglou I, Edelman RR. Fast projective carotid MR angiography using arterial spin-labeled balanced SSFP. J Magn Reson Imaging. 2008 Sep;28(3):778-82. doi: 10.1002/jmri.21476.
71. Dharmakumar R, Koktzoglou I, Tang R, Harris KR, Beohar N, Li D. Off-resonance positive contrast imaging of a passive endomyocardial catheter in swine. Phys Med Biol. 2008 Jul 7;53(13):N249-57. doi: 10.1088/0031-9155/53/13/N02. Epub 2008 Jun 19.
72. Koktzoglou I, Kirpalani A, Carroll TJ, Li D, Carr JC. Dark-blood MRI of the thoracic aorta with 3D diffusion-prepared steady-state free precession: initial clinical evaluation. AJR Am J Roentgenol. 2007 Oct;189(4):966-72. doi: 10.2214/AJR.07.2428.
73. Koktzoglou I, Li D, Dharmakumar R. Dephased FLAPS for improved visualization of susceptibility-shifted passive devices for real-time interventional MRI. Phys Med Biol. 2007 Jul 7;52(13):N277-86. doi: 10.1088/0031-9155/52/13/N01. Epub 2007 May 25.
74. Dharmakumar R, Koktzoglou I, Li D. Factors influencing fast low angle positive contrast steady-state free precession (FLAPS) magnetic resonance imaging. Phys Med Biol. 2007 Jun 7;52(11):3261-73. doi: 10.1088/0031-9155/52/11/021. Epub 2007 May 15.
75. Koktzoglou I, Chung YC, Carroll TJ, Simonetti OP, Morasch MD, Li D. Three-dimensional black-blood MR imaging of carotid arteries with segmented steady-state free precession: initial experience. Radiology. 2007 Apr;243(1):220-8. doi: 10.1148/radiol.2431060310.
76. Koktzoglou I, Li D. Submillimeter isotropic resolution carotid wall MRI with swallowing compensation: imaging results and semiautomated wall morphometry. J Magn Reson Imaging. 2007 Apr;25(4):815-23. doi: 10.1002/jmri.20849.
77. Koktzoglou I, Li D. Diffusion-prepared segmented steady-state free precession: Application to 3D black-blood cardiovascular magnetic resonance of the thoracic aorta and carotid artery walls. J Cardiovasc Magn Reson. 2007;9(1):33-42. doi: 10.1080/10976640600843413.
78. Dharmakumar R, Koktzoglou I, Li D. Generating positive contrast from off-resonant spins with steady-state free precession magnetic resonance imaging: theory and proof-of-principle experiments. Phys Med Biol. 2006 Sep 7;51(17):4201-15. doi: 10.1088/0031-9155/51/17/006. Epub 2006 Aug 8.
79. Koktzoglou I, Chung YC, Mani V, Carroll TJ, Morasch MD, Mizsei G, Simonetti OP, Fayad ZA, Li D. Multislice dark-blood carotid artery wall imaging: a 1.5 T and 3.0 T comparison. J Magn Reson Imaging. 2006 May;23(5):699-705. doi: 10.1002/jmri.20563.
80. Koktzoglou I, Harris KR, Tang R, Kane BJ, Misselwitz B, Weinmann HJ, Lu B, Nagaraj A, Roth SI, Carroll TJ, McPherson DD, Li D. Gadofluorine-enhanced magnetic resonance imaging of carotid atherosclerosis in Yucatan miniswine. Invest Radiol. 2006 Mar;41(3):299-304. doi: 10.1097/01.rli.0000188362.12555.62.
81. Koktzoglou I, Simonetti O, Li D. Coronary artery wall imaging: initial experience at 3 Tesla. J Magn Reson Imaging. 2005 Feb;21(2):128-32. doi: 10.1002/jmri.20232.

U.S. Patents:

• “System and Method for Semi-Projective Quantitative Flow Imaging Using Accelerated Arterial Spin-Labeled Cine MRI” United States Patent 10,859,658
• “System and Method for Fast Interrupted Steady-State (FISS) MRI” United States Patent 10,845,447
• “Data acquisition acceleration in magnetic resonance angiography applications using magnetization-prepared simultaneous multi-slice acquisition” United States Patent 10,517,490.
• "System and method for hybrid radiofrequency labeling for magnetic resonance imaging" US Patent Number 10,413,213
• "Systems and methods for imaging vascular calcifications with magnetic resonance imaging" US Patent Number 10,401,459
• "System and method for neutral contrast magnetic resonance imaging of calcifications" US Patent Number 10,362,961
• "Background-suppressed, reduced field-of-view radial magnetic resonance imaging" US Patent Number 10,188,355
• "Systems and methods for efficient radial magnetic resonance imaging with azimuthal equidistant projections" US Patent Number 10,120,048
• "System and method for accelerated angiographic magnetic resonance imaging" US Patent Number 10,061,006
• "System and method for imaging of the vascular components with temporal information and suppressed blood pools using magnetic resonance imaging" US Patent Number 9,968,276
• "System and method for imaging of vascular structures using non-contrast enhanced magnetic resonance imaging" US Patent Number 9,507,003
• "System and method for ungated non-contrast enhanced magnetic resonance angiography" US Patent Number 9,113,810
• "System and method for phase contrast imaging with improved efficiency" US Patent Number 8,838,204
• "Method for non-contrast enhanced magnetic resonance angiography" US Patent Number 8,744,551
• "Time resolved spin labeled MRI cineangiography" US Patent Number 8,441,257
• "Parallel-accelerated complex subtraction MRI" US Patent Number 8,274,284
• "System and method for ghost magnetic resonance imaging" US Patent Number 8,154,287

Peer Reviewer Service for the Following Journals:

• Magnetic Resonance in Medicine
• Journal of Magnetic Resonance Imaging
• Journal of Cardiovascular Magnetic Resonance
• Radiology
• Circulation: Cardiovascular Imaging
• American Journal of Roentgenology
• Magn. Reson. Materials in Physics Biology & Medicine
• PLOS ONE
• NMR in Biomedicine
• Clinical Medicine Cardiology
• European Journal of Nuclear Medicine and Molecular Imaging
• Korean Journal of Radiology
• Medical Physics
• Magnetic Resonance Imaging
• American Journal of Neuroradiology
• Frontiers Neuroscience
• IEEE Access
• BMC Medical Imaging
• Journal of NeuroInterventional Surgery
• Scientific Reports