GOG-0199 Prospective Study of Risk-Reducing Salpingo-oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian Cancer
Aims: We are following a group of women over time to better understand the incidence of ovarian cancer, breast cancer, primary peritoneal carcinoma (an ovarian-like cancer), and all cancer in women at increased risk of ovarian cancer. We are placing special emphasis on women who are known BRCA1/2 mutation carriers.  In addition, we plan to determine the prevalence of undetected ovarian cancer and fallopian tube cancer among women undergoing prophylactic salpingo-oophorectomy (removal of the fallopian tubes and ovaries). We are looking at changes in quality of life issues over time by comparing women undergoing screening and women who have undergone salpingo-oophorectomy. We recruited more subjects than any of the 124 international sites; our enrollment accounted for about 9% of study accrual.
Principal Investigator: Gustavo Rodriguez, MD
Open to Enrollment: No

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