Although one of the main areas of focus for dynamic system modeling in the Center for the Study of Complex Disease is gastrointestinal disease, the value of dynamic system models is far greater. Dynamic system modeling has the potential to be applied to a wide array of complex diseases to improve medical treatment, optimize quality, and generally improve patients’ experiences with healthcare.

  • Gastrointestinal absorption of phosphate in patients with kidney failure
  • Improving efficiency in labor and delivery units
  • Inclusion of correction factors for calculating areas under the curve and residence time, a measure of volume distribution and clearance, in pharmacokinetic studies
  • Drug-induced changes of the QT interval on the EKG
  • Neural networks associated with alcohol abuse
  • Randomness of events using a “light switch” analogy
  • Pharmacokinetics of gadolinium in breast imaging