Gordon W. Nuber, M.D.

Gordon W. Nuber, M.D.

Gordon W. Nuber, M.D.

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Conditions & Procedures


ACL Reconstruction, Arthroscopy, Rotator Cuff Repair

General Information




NorthShore Medical Group


Shoulder Arthroscopy, Knee Arthroscopy, Elbow Arthroscopy



Board Certified

Orthopaedic Surgery

Clinical Service

Sports Medicine

Education, Training & Fellowships

Medical School

Wayne State University School of Medicine, 1978


McGaw Medical Center of Northwestern University, 1979


McGaw Medical Center of Northwestern University, 1983


Kerlan-Jobe Orthopaedic Clinic, 1984



NOI NorthShore Orthopedics Chicago

680 N Lake Shore Dr
Ste 924
Chicago, IL 60611
847.866.7846 866.954.5787 fax This location is wheelchair accessible.

NOI NorthShore Orthopedics Glenview

2501 Compass Rd
Ste 125
Glenview, IL 60026
847.866.7846 866.954.5787 fax This location is wheelchair accessible.


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  • The Impact of a Cervical Spine Diagnosis on the Careers of National Football League Athletes.

    Spine 2014 Apr 8

    Authors: Schroeder GD,
    Study Design. Cohort StudyObjective. To determine the effect of cervical spine pathology on athletes entering the NFL.Background. The association of symptomatic cervical spine pathology with American football athletes has been described, however, it is unknown how pre-existing cervical spine pathology affects career performance of a NFL player.Methods. The medical evaluations and imaging reports of American football athletes from 2003-2011 during the combine were evaluated. Athletes with a cervical spine diagnosis were matched to controls, and career statistics were compiled.Results. Of a total of 2,965 evaluated athletes, 143 players met the inclusion criteria. Athletes who attended the NFL combine without a cervical spine diagnosis were more likely to be drafted than those with a diagnosis (p = 0.001). Players with a cervical spine diagnosis had a decreased total games played (p = 0.01). There was no difference in the number of games started (p = 0.08) or performance score (p = 0.38). In 10 athletes with a sagittal canal diameter <10mm, there was no difference in years, games played, games started, or performance score (p > 0.24). No neurologic injury occurred during their careers. In seven players who were drafted with a history of cervical spine surgery (4 ACDF, 2 foraminotomy, 1 suboccipital craniectomy with a C1 laminectomy), there was no difference in career longevity or performance when compared to matched controls.Conclusion. This study suggests athletes with pre-existing cervical spine pathology were less likely to be drafted compared to controls. Players with pre-existing cervical spine pathology demonstrated a shorter career compared to those without, however, statistically-based performance and numbers of games started were not different. Players with cervical spinal stenosis and those with a history of previous surgery demonstrated no difference in performance-based outcomes and no reports of neurologic injury during their careers.
    PMID: 24718072 [PubMed - as supplied by publisher]
  • Acromioclavicular joint injuries in the national football league: epidemiology and management.

    The American journal of sports medicine 2013 Dec

    Authors: Lynch TS,
    Previous studies investigating acromioclavicular (AC) joint injuries in professional American football players have only been reported on quarterbacks during the 1980s and 1990s. These injuries have not been evaluated across all position players in the National Football League (NFL).
    The purpose of this study was 4-fold: (1) to determine the incidence of AC joint injuries among all NFL position players; (2) to investigate whether player position, competition setting, type of play, and playing surface put an athlete at an increased risk for this type of injury; (3) to determine the incidence of operative and nonoperative management of these injuries; and (4) to compare the time missed for injuries treated nonoperatively to the time missed for injuries requiring surgical intervention.
    Descriptive epidemiological study.
    All documented injuries of the AC joint were retrospectively analyzed using the NFL Injury Surveillance System (NFLISS) over a 12-season period from 2000 through 2011. The data were analyzed by the anatomic location, player position, field conditions, type of play, requirement of surgical management, days missed per injury, and injury incidence.
    Over 12 NFL seasons, there were a total of 2486 shoulder injuries, with 727 (29.2%) of these injuries involving the AC joint. The overall rate of AC joint injuries in these athletes was 26.1 injuries per 10,000 athlete exposures, with the majority of these injuries occurring during game activity on natural grass surfaces (incidence density ratio, 0.79) and most often during passing plays. These injuries occurred most frequently in defensive backs, wide receivers, and special teams players; however, the incidence of these injuries was greatest in quarterbacks (20.9 injuries per 100 players), followed by special teams players (20.7/100) and wide receivers (16.5/100). Overall, these athletes lost a mean of 9.8 days per injury, with quarterbacks losing the most time to injury (mean, 17.3 days). The majority of these injuries were low-grade AC joint sprains that were treated with nonoperative measures; only 13 (1.7%) required surgical management. Players who underwent surgical management lost a mean of 56.2 days.
    Shoulder injuries, particularly those of the AC joint, occur frequently in the NFL. These injuries can result in time lost but rarely require operative management. Quarterbacks had the highest incidence of injury; however, this incidence is lower than in previous investigations that evaluated these injuries during the 1980s and 1990s.
    PMID: 24057030 [PubMed - as supplied by publisher]
  • Nerve block of the infrapatellar branch of the saphenous nerve in knee arthroscopy: a prospective, double-blinded, randomized, placebo-controlled trial.

    The Journal of bone and joint surgery. American volume 2013 Aug 21

    Authors: Hsu LP,
    With the rising use of outpatient knee arthroscopy over the past decade, interest in peripheral nerve blocks during arthroscopy has increased. Femoral nerve blocks are effective but are associated with an inherent risk of the patient falling postoperatively because of quadriceps weakness. We studied blocks of the infrapatellar branch of the saphenous nerve, which produce analgesia in the knee that is similar to that resulting from a femoral nerve block but without associated quadriceps weakness.
    Thirty-four patients were enrolled into each arm of this prospective, randomized, double-blinded trial comparing 10 mL of 0.25% bupivacaine used as a block of the infrapatellar branch of the saphenous nerve with a placebo during simple knee arthroscopy. Immediate outcome measures included Numeric Rating Scale (NRS) pain scores (0 to 10 points), mobility and discharge times, opioid usage, subjective adverse side effects, and forty-eight-hour anesthesia recovery surveys. Short-term measures included one-week and twelve-week Lysholm knee scores.
    No adverse effects or increased quadriceps weakness were observed following use of the nerve block. Improvement in early NRS scores and subjective nausea (p = 0.03) were detected. Patients for whom the block was successful also had improved twelve-week Lysholm knee scores (p = 0.04). No differences in opioid usage, mobility time, forty-eight-hour anesthesia recovery scores, or one-week Lysholm knee scores were found.
    No significant adverse effect or disadvantage was identified for blocks of the infrapatellar branch of the saphenous nerve used in simple knee arthroscopy. In addition to decreased early NRS scores and nausea, blocks of the infrapatellar branch of the saphenous nerve demonstrated potential benefit at twelve weeks after simple knee arthroscopy.
    PMID: 23965696 [PubMed - as supplied by publisher]
  • Biomechanical comparison of 3 methods to repair pectoralis major ruptures.

    The American journal of sports medicine 2012 Jul

    Authors: Rabuck SJ,
    Pectoralis major ruptures are closely associated with weight lifting and participation in sports. The anatomy of the pectoralis major tendon is unique with an elongated thin footprint requiring multiple points of fixation to restore the native anatomy. Multiple options exist for tendon repairs, but the strongest construct has yet to be identified.
    The intent of this study was to compare the load to failure of bone trough, cortical button, and suture anchor repairs of the pectoralis major tendon in the extended and abducted position.
    Controlled laboratory study.
    Thirty fresh-frozen cadaveric shoulders were divided equally into 3 groups based on the repair technique to be performed. Bone mineral density of the surgical neck of the proximal humerus was assessed before each repair. Bone trough, suture anchor, and cortical button repairs were performed as dictated by computerized randomization. Each specimen was loaded to failure and mode of failure was noted.
    The majority of failures occurred through the suture used for tendon repair. One specimen in the bone trough group failed via fracture of the proximal humerus. The suture anchor group failed at the implant in 5 of 9 specimens and through the suture in 4 of 9 specimens. Load to failure was greatest in bone trough repairs at 596 N, followed by cortical button at 494 N, and finally suture anchor repairs with 383 N. Load to failure was significantly greater in the bone trough group when compared with suture anchor repairs (P = .007). No correlation was found between bone mineral density and load to failure.
    Bone trough repair of the pectoralis major tendon was stronger than suture anchor repair.
    Identification of the strongest repair may help guide surgical repair.
    PMID: 22679296 [PubMed - as supplied by publisher]
  • The anterior deltoid's importance in reverse shoulder arthroplasty: a cadaveric biomechanical study.

    Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] 2013 Mar

    Authors: Schwartz DG,
    Frequently, patients who are candidates for reverse shoulder arthroplasty have had prior surgery that may compromise the anterior deltoid muscle. There have been conflicting reports on the necessity of the anterior deltoid thus it is unclear whether a dysfunctional anterior deltoid muscle is a contraindication to reverse shoulder arthroplasty. The purpose of this study was to determine the 3-dimensional (3D) moment arms for all 6 deltoid segments, and determine the biomechanical significance of the anterior deltoid before and after reverse shoulder arthroplasty.
    Eight cadaveric shoulders were evaluated with a 6-axis force/torque sensor to assess the direction of rotation and 3D moment arms for all 6 segments of the deltoid both before and after placement of a reverse shoulder prosthesis. The 2 segments of anterior deltoid were unloaded sequentially to determine their functional role.
    The 3D moment arms of the deltoid were significantly altered by placement of the reverse shoulder prosthesis. The anterior and middle deltoid abduction moment arms significantly increased after placement of the reverse prosthesis (P < .05). Furthermore, the loss of the anterior deltoid resulted in a significant decrease in both abduction and flexion moments (P < .05).
    The anterior deltoid is important biomechanically for balanced function after a reverse total shoulder arthroplasty. Losing 1 segment of the anterior deltoid may still allow abduction; however, losing both segments of the anterior deltoid may disrupt balanced abduction. Surgeons should be cautious about performing reverse shoulder arthroplasty in patients who do not have a functioning anterior deltoid muscle.
    PMID: 22608931 [PubMed - as supplied by publisher]
  • Biologic and pharmacologic augmentation of rotator cuff repairs.

    The Journal of the American Academy of Orthopaedic Surgeons 2011 Oct

    Authors: Edwards SL,
    As rotator cuff repair techniques have improved, failure of the tendon to heal to the proximal humerus is less likely to occur from weak tendon-to-bone fixation. More likely causes of failure include biologic factors such as intrinsic tendon degeneration, fatty atrophy, fatty infiltration of muscle, and lack of vascularity of the tendons. High failure rates have led to the investigation of biologic augmentation to potentially enhance the healing response. Histologic studies have shown that restoration of the rotator cuff footprint during repair can help reestablish the enthesis. In animal models, growth factors and their delivery scaffolds as well as tissue engineering have shown promise in decreasing scar tissue while maintaining biomechanical strength. Platelet-rich plasma may be a safe adjuvant to rotator cuff repair, but it has not been shown to improve healing or function. Many of these strategies need to be further defined to permit understanding of, and to optimize, the biologic environment; in addition, techniques need to be refined for clinical use.
    PMID: 21980023 [PubMed - as supplied by publisher]
  • Efficacy of preoperative home use of 2% chlorhexidine gluconate cloth before shoulder surgery.

    Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] 2011 Sep

    Authors: Murray MR,
    Deep infection after shoulder surgery is a rare but devastating problem. This study tested the hypothesis that the home application of a 2% chlorhexidine gluconate cloth before shoulder surgery would be more efficacious than a standard shower of soap and water at decreasing the preoperative cutaneous levels of pathogenic bacteria on the shoulder.
    This randomized, prospective study evaluated 100 consecutive patients undergoing shoulder surgery. Patients were randomly assigned to use 2% chlorhexidine gluconate-impregnated cloths (treatment group) or to shower with soap and water before surgery (control group). Cutaneous cultures were taken from the patients'shoulders in the preoperative holding area. Patients were monitored for 2 months postoperatively for clinical signs of infection.
    In the treatment group vs the control group, the overall positive culture rate was 66% vs 94% (P = .0008), and the positive culture rate for coagulase-negative Staphylococcus was 30% vs 70% (P = .0001). The positive culture rate for Propionibacterium acnes was 46% in the treatment group vs 58% in the control group (P = .32). No infections occurred in any patients at a minimum of 2-months after surgery.
    The use of the 2% chlorhexidine cloth was effective at decreasing overall bacterial culture rates before shoulder surgery and was particularly effective at decreasing the quantity of coagulase-negative Staphylococcus, a known causative agent of postoperative shoulder infections.
    Use of chlorhexidine impregnated cloths prior to shoulder surgery may be a useful adjunct to presently used infection prevention strategies.
    PMID: 21612945 [PubMed - as supplied by publisher]
  • Developing a 6-DOF robot to investigate multi-axis ACL injuries under valgus loading coupled with tibia internal rotation.

    Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2010

    Authors: Ren Y, Jacobs BJ, Nuber GW, Koh JL, Zhang LQ,
    Anterior cruciate ligament (ACL) injuries have become more common in recent years as more young people participate in risky sporting activities [1]. Most ACL injuries occur as a result of noncontact mechanisms. Previous in vitro studies of ACL strain have found significant increases in ACL strain primarily with anterior directed force on the tibia relative to the femur and with internal rotation and often with valgus torque [2,3]. However, there remains significant controversy over the mechanisms of ACL failure and the forces on the knee that lead to injury. Some studies have also shown that isolated valgus loading may not load the ACL strongly. The goal of this study was to investigate the mechanism underlying valgus-related ACL injuries. An improved understanding of ACL failure may lead to improved ACL injury prevention programs. A novel 6 degrees of freedom (DOF) knee driving robot was developed in this study with a unique multi-axis simultaneous torque/position control. It was found that pure valgus torque caused a torque that internally rotated the tibia and thus increased ACL strain markedly, which may be an important mechanism underlying the rather common seemingly valgus-related ACL injuries.
    PMID: 21097089 [PubMed - as supplied by publisher]
  • Efficacy and safety of hylan G-F 20 for symptomatic glenohumeral osteoarthritis: a prospective, pilot study.

    PM & R : the journal of injury, function, and rehabilitation 2010 Apr

    Authors: Brander VA,
    To determine the safety and efficacy of 2 intra-articular, fluoroscopically guided hylan G-F 20 injections for painful glenohumeral osteoarthritis.
    This study was a prospective open-label pilot investigation with both U.S. Food and Drug Administration and institutional review board approval.
    Private, outpatient practice within a tertiary care, university medical school.
    Thirty-six subjects with moderate to severe glenohumeral osteoarthritis, with pain (visual analog scale [VAS] 40 mm or greater) despite following a 3-month standard, nonsurgical treatment program.
    Two injections of 2 mL hylan G-F 20, under fluoroscopic guidance confirmed by arthrography, 2 weeks apart. No new treatments were allowed during the course of the study. Analgesics were discontinued 24 hours before visits.
    Data collected were radiographs; rotator cuff integrity as determined with magnetic resonance imaging; VAS for pain at rest, at night, and with activity; and shoulder-related quality of life (Western Ontario Rotator Cuff Index [WORC]). Subjects were re-evaluated after each injection and at 6 weeks, 3 months, and 6 months. Changes from baseline for VAS and WORC were recorded in Excel and analyzed using SPSS. Intent-to-treat analysis was performed. The type and severity of adverse events were recorded.
    Mean VAS at baseline was 63 mm (SD 14.5). Clinically (>or=20% improvement) and statistically significant improvements (P < .001) in VAS pain were seen at 6 weeks, 3 months, and 6 months. Mean improvement in WORC at 6 months was 16.5 (P < .01), with most gains in "lifestyle" and "emotion" questions. Age, gender, body mass index, and rotator cuff pathology did not correlate with response. Three subjects described heightened pain for a few days after injections. Three subjects reported greater pain at 6 months and were unsatisfied. Four experienced no effect of treatment. There were no inflammatory reactions.
    Two hylan G-F 20 injections improved pain and function, and should be considered as part of a multimodal shoulder osteoarthritis treatment program.
    PMID: 20430327 [PubMed - as supplied by publisher]
  • Supramolecular design of self-assembling nanofibers for cartilage regeneration.

    Proceedings of the National Academy of Sciences of the United States of America 2010 Feb 23

    Authors: Shah RN,
    Molecular and supramolecular design of bioactive biomaterials could have a significant impact on regenerative medicine. Ideal regenerative therapies should be minimally invasive, and thus the notion of self-assembling biomaterials programmed to transform from injectable liquids to solid bioactive structures in tissue is highly attractive for clinical translation. We report here on a coassembly system of peptide amphiphile (PA) molecules designed to form nanofibers for cartilage regeneration by displaying a high density of binding epitopes to transforming growth factor beta-1 (TGFbeta-1). Growth factor release studies showed that passive release of TGFbeta-1 was slower from PA gels containing the growth factor binding sites. In vitro experiments indicate these materials support the survival and promote the chondrogenic differentiation of human mesenchymal stem cells. We also show that these materials can promote regeneration of articular cartilage in a full thickness chondral defect treated with microfracture in a rabbit model with or even without the addition of exogenous growth factor. These results demonstrate the potential of a completely synthetic bioactive biomaterial as a therapy to promote cartilage regeneration.
    PMID: 20133666 [PubMed - as supplied by publisher]
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