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Aldosterone receptor antagonists, such as spironolactone, are another type of potassium-sparing diuretic used for heart failure. For more information on this medicine, see Aldosterone Receptor Antagonists: Diuretics for Heart Failure.
Diuretics stimulate the kidneys to remove
more water and salt (sodium) from the body. This can help relieve swelling that happens because of heart failure.
These medicines are used if you have heart failure symptoms
of fluid buildup (such as difficulty breathing or swelling in your legs and
ankles). Diuretics are often used with ACE inhibitors and may be combined with
Diuretics help rid the body of extra
fluid and sodium. They can help relieve some symptoms of heart failure such as swelling in the legs.1
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
or other emergency services right away if you have:
Call your doctor right away if you have symptoms of changes in potassium levels:
Other side effects of this medicine include:
See Drug Reference for a full list
of side effects. (Drug Reference is not available in all systems.)
You may feel more tired or need to urinate more often when you start taking this medicine. These effects typically occur less after you have taken the medicine for a while. If the increase in urine interferes with your sleep or daily activities, ask your doctor to help you plan a schedule for taking the medicine.
You will likely have regular blood tests to monitor how the medicine is working in your body. Your doctor will let you know when you need to have the tests.
Ask your doctor if you need to take a potassium supplement or if you need to watch the amount of potassium in your diet. If you take a loop diuretic or thiazide diuretic, your doctor may suggest you get extra potassium because these medicines lower your potassium levels. But if you take a potassium-sparing diuretic, you do not need to get extra potassium in your diet.
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
For tips on taking medicine for heart failure, see:
If you are pregnant, breast-feeding, or trying to get pregnant, do not use any medicines unless your doctor tells you to. Some medicines can harm your baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all your doctors know that you are pregnant, breast-feeding, or planning to get pregnant.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Drugs for treatment of chronic heart failure (2009). Treatment Guidelines From The Medical Letter, 7(83): 53–56.
April 26, 2012
Rakesh K. Pai, MD, FACC - Cardiology, Electrophysiology
& Margaret Hetherington, PHM, BsC - Pharmacy
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