« Previous Page

paclitaxel protein-bound

paclitaxel protein-bound

Pronunciation: PAK li TAX el PRO teen-bound

Brand: Abraxane

What is the most important information I should know about paclitaxel protein-bound?

Multum nopreg

Do not use paclitaxel protein-bound if you are pregnant. It could harm the unborn baby.

Multum nopreg

Use birth control to prevent pregnancy while you are receiving paclitaxel protein-bound, whether you are a man or a woman. Paclitaxel protein-bound use by either parent may cause birth defects.

Multum donot

You should not use paclitaxel protein-bound if you are allergic to it, or if you have a low white blood cell count.

Before you receive this medication, tell your doctor if you have kidney disease, liver disease, heart disease, or bone marrow suppression.

To make sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor.

Multum donot

Call your doctor at once if you have a serious side effect such as fever, chills, flu symptoms, mouth sores, easy bruising or bleeding, pale skin, feeling light-headed or short of breath, swelling or rapid weight gain, chest pain, sudden cough, rapid heart rate, or trouble breathing.

What is paclitaxel protein-bound?

Paclitaxel protein-bound is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Paclitaxel protein-bound is used in the treatment of breast cancer.

Paclitaxel protein-bound is usually given after other cancer medicines have been tried without successful treatment.

Paclitaxel protein-bound may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving paclitaxel protein-bound?

Multum donot

You should not use paclitaxel protein-bound if you are allergic to it, or if you have a low white blood cell count.

To make sure you can safely receive paclitaxel protein-bound, tell your doctor if you have any of these other conditions:

  • kidney disease;
  • liver disease;
  • heart disease, heart rhythm disorder; or
  • bone marrow suppression.
Multum nopreg

FDA pregnancy category D. Do not use paclitaxel protein-bound if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Multum nopreg

Use birth control to prevent pregnancy while you are receiving paclitaxel protein-bound, whether you are a man or a woman. Paclitaxel protein-bound use by either parent may cause birth defects.

Multum nobrfeed

It is not known whether paclitaxel protein-bound passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving paclitaxel protein-bound.

How is paclitaxel protein-bound given?

Paclitaxel protein-bound is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Paclitaxel protein-bound must be given slowly, and the IV infusion can take at least 30 minutes to complete.

Paclitaxel protein-bound is usually given once every 3 weeks. Follow your doctor's dosing instructions very carefully.

Multum emt

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when paclitaxel protein-bound is injected.

To make sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your paclitaxel protein-bound injection.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while using paclitaxel protein-bound?

Multum emt

Paclitaxel protein-bound can be harmful if it gets in your eyes, mouth, or nose, or on your skin. If skin contact occurs, wash the area with soap and water or rinse the eyes thoroughly with plain water.

What are the possible side effects of paclitaxel protein-bound?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • fever, chills, body aches, flu symptoms, sores in your mouth and throat;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • feeling like you might pass out;
  • feeling short of breath (even with mild exertion), swelling, rapid weight gain;
  • chest pain, sudden cough, wheezing, trouble breathing, fast heart rate; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • numbness or tingly feeling;
  • muscle or joint pain;
  • nausea, vomiting;
  • diarrhea; or
  • hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect paclitaxel protein-bound?

Tell your doctor about all other medicines you use, especially:

  • bosentan (Tracleer);
  • conivaptan (Vaprisol);
  • imatinib (Gleevec);
  • isoniazid (for treating tuberculosis);
  • montelukast (Singulair) or zafirlukast (Accolate);
  • selegiline (Eldepryl, Emsam, Zelapar);
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), rifampin (Rifater, Rifadin, Rifamate), or telithromycin (Ketek);
  • an antidepressant such as nefazodone or fluoxetine (Prozac);
  • antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
  • a blood thinner such as warfarin (Coumadin, Jantoven);
  • cancer medication such as paclitaxel (Taxol) or tamoxifen (Soltamox);
  • heart or blood pressure medications such as amiodarone (Cordarone, Pacerone), carvedilol (Coreg), diltiazem (Cardizem, Cartia, Dilacor, Diltia, Diltzac, Taztia, Tiazac), felodipine (Plendil), losartan (Hyzaar, Cozaar), nifedipine (Nifedical, Procardia), torsemide (Demadex), verapamil (Calan, Covera, Isoptin, Verelan), and others;
  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), saquinavir (Invirase), or ritonavir (Norvir, Kaletra);
  • seizure medications such as fosphenytoin (Cerebyx), or phenytoin (Dilantin);
  • oral diabetes medication such as glimepiride (Amaryl), glipizide (Glucotrol), nateglinide (Starlix), pioglitazone (Actos, Actoplus Met), repaglinide (Prandin), rosiglitazone (Avandia, Avandamet), or tolbutamide (Orinase); or
  • sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others).

This list is not complete and other drugs may interact with paclitaxel protein-bound. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about paclitaxel protein-bound.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2013 Cerner Multum, Inc. Version: 6.01. Revision date: 6/12/2012.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.

This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.

× Alternate Text