amlodipine and benazepril

Pronunciation: am LOE di peen and ben AY ze pril

Brand: Lotrel

Amlodipine-Benazepril 10 mg-20 mg-TEV

slide 1 of 13, Amlodipine-Benazepril 10 mg-20 mg-TEV,

capsule, blue, imprinted with TEVA 7373

Image of Amlodipine-Benazepril 10 mg-20 mg-TEV
slide 1 of 13
    

Amlodipine-Benazepril 10 mg-40 mg-TEV

slide 2 of 13, Amlodipine-Benazepril 10 mg-40 mg-TEV,

capsule, blue, imprinted with TEVA, 7671

Image of Amlodipine-Benazepril 10 mg-40 mg-TEV
slide 2 of 13
    

Amlodipine-Benazepril 2.5 mg-10 mg-TEV

slide 3 of 13, Amlodipine-Benazepril 2.5 mg-10 mg-TEV,

capsule, white, imprinted with TEVA, 7370

Image of Amlodipine-Benazepril 2.5 mg-10 mg-TEV
slide 3 of 13
    

Amlodipine-Benazepril 5 mg-10 mg-TEV

slide 4 of 13, Amlodipine-Benazepril 5 mg-10 mg-TEV,

capsule, orange/white, imprinted with TEVA, 7371

Image of Amlodipine-Benazepril 5 mg-10 mg-TEV
slide 4 of 13
    

Amlodipine-Benazepril 5 mg-20 mg-TEV

slide 5 of 13, Amlodipine-Benazepril 5 mg-20 mg-TEV,

capsule, pink/white, imprinted with TEVA 7372

Image of Amlodipine-Benazepril 5 mg-20 mg-TEV
slide 5 of 13
    

Amlodipine-Benazepril 5 mg-40 mg-TEV

slide 6 of 13, Amlodipine-Benazepril 5 mg-40 mg-TEV,

capsule, blue, imprinted with TEVA, 7670

Image of Amlodipine-Benazepril 5 mg-40 mg-TEV
slide 6 of 13
    

Lotrel 10 mg-20 mg

slide 7 of 13, Lotrel 10 mg-20 mg,

capsule, purple, imprinted with LOTREL 0364

Image of Lotrel 10 mg-20 mg
slide 7 of 13
    

Lotrel 10-40 mg

slide 8 of 13, Lotrel 10-40 mg,

capsule, blue, imprinted with Lotrel 0379

Image of Lotrel 10-40 mg
slide 8 of 13
    

Lotrel 2.5-10mg

slide 9 of 13, Lotrel 2.5-10mg,

capsule, white, imprinted with LOTREL 2255

Image of Lotrel 2.5-10mg
slide 9 of 13
    

Lotrel 5 mg-10 mg

slide 10 of 13, Lotrel 5 mg-10 mg,

capsule, orange, imprinted with LOTREL 2260

Image of Lotrel 5 mg-10 mg
slide 10 of 13
    

Lotrel 5-10mg

slide 11 of 13, Lotrel 5-10mg,

capsule, brown, imprinted with LOTREL 2260

Image of Lotrel 5-10mg
slide 11 of 13
    

Lotrel 5-20

slide 12 of 13, Lotrel 5-20,

capsule, pink, imprinted with LOTREL 2265

Image of Lotrel 5-20
slide 12 of 13
    

Lotrel 5-40 mg

slide 13 of 13, Lotrel 5-40 mg,

capsule, blue, imprinted with Lotrel, 0384

Image of Lotrel 5-40 mg
slide 13 of 13
    

What is the most important information I should know about amlodipine and benazepril?

Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Amlodipine and benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not use this medicine if you have ever had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction).

If you have diabetes, do not use amlodipine and benazepril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

What is amlodipine and benazepril?

Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow.

Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Benazepril also widens blood vessels and also prevents the body from retaining water.

Amlodipine and benazepril is a combination medicine used to treat high blood pressure (hypertension).

Amlodipine and benazepril may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking amlodipine and benazepril?

You should not use this medicine if:

  • you are allergic to amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide) or benazepril (Lotensin);
  • you have ever had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction); or
  • you are allergic to any other ACE inhibitor, such as captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

If you have diabetes, do not use amlodipine and benazepril together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

You may also need to avoid taking amlodipine and benazepril with aliskiren if you have kidney disease.

To make sure amlodipine and benazepril is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);
  • liver disease;
  • heart disease or congestive heart failure;
  • a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;
  • if you are on a low-salt diet.

Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Amlodipine and benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.

Amlodipine and benazepril can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

How should I take amlodipine and benazepril?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Amlodipine and benazepril can be taken with or without food. Take the medicine at the same time each day.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. Drink plenty of water each day while you are taking this medicine.

Your blood pressure will need to be checked often. You may also need frequent blood tests at your doctor's office.

If you need surgery, tell the surgeon ahead of time that you are using amlodipine and benazepril. You may need to stop using the medicine for a short time.

You may have very low blood pressure while taking this medicine. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. Prolonged illness can lead to a serious electrolyte imbalance, making it dangerous for you to use amlodipine and benazepril.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking amlodipine and benazepril?

Drinking alcohol with this medicine can cause side effects.

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Do not use salt substitutes or potassium supplements while taking amlodipine and benazepril, unless your doctor has told you to.

What are the possible side effects of amlodipine and benazepril?

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American.

Some side effects may not occur until after you have used the medicine for several months.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • swelling in your hands or feet, rapid weight gain;
  • new or worsened chest pain;
  • fever, chills, sore throat, body aches, flu symptoms;
  • high potassium --nausea, slow or unusual heart rate, weakness, loss of movement; or
  • liver problems --nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • cough;
  • dizziness; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect amlodipine and benazepril?

Many drugs can interact with amlodipine and benazepril. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • gold injections to treat arthritis;
  • a shot for bee-sting allergy;
  • lithium;
  • simvastatin;
  • a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
  • a potassium supplement such as K-Dur, Klor-Con;
  • salt substitutes that contain potassium; or
  • a diuretic (water pill).

This list is not complete and many other drugs can interact with amlodipine and benazepril. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about amlodipine and benazepril.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2015 Cerner Multum, Inc. Version: 9.01. Revision date: 1/21/2015.

Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by clicking on this link.