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Dis Mon. 2011 Mar;57(3):127-34
Authors: Dalvi A, Mercury MG
PMID: 21447421 [PubMed - indexed for MEDLINE]
Dis Mon. 2007 May;53(5):296-301
Authors: Mercury MG, Tschan W, Kehoe R, Kuechler A
PMID: 17656191 [PubMed - indexed for MEDLINE]
Dis Mon. 2007 Mar;53(3):138-41
Authors: Mercury MG, Kehoe R, Tschan W
PMID: 17544642 [PubMed - indexed for MEDLINE]
Clin Neuropsychol. 2003 Aug;17(3):322-30
Authors: Demakis GJ, Mercury MG, Sweet JJ, Rezak M, Eller T, Vergenz S
This study examined qualitative aspects of phonemic and semantic fluency before and after unilateral pallidotomy in patients with intractable Parkinson's Disease (PD). Specifically, clustering (number of similar words generated sequentially) and switching (number of changes or switches from one cluster to another) were evaluated for both fluency tasks. Twenty-five PD patients participated and were grouped according to whether they improved or declined on each of the fluency measures after surgery. Decliners evidenced decreased switching, but not clustering, suggesting difficulties with set-shifting and cognitive flexibility rather than a diminished semantic store of information or retrieval difficulties. Though consistent with hypotheses about difficulties with executive processing after pallidotomy, a series of correlational analyses with composite measures of neuropsychological functioning (attention, language, executive processing, and memory) suggest caution in interpreting these findings. In these analyses, clustering was not meaningfully related to any of the composites whereas switching was significantly and positively related to the composites; this pattern emerged, for the most part, on both fluency measures before and after surgery. Switching, but not clustering, was also significantly and positively correlated with total words generated on both semantic and phonemic fluency. Switching changes across time were also related to DRS changes post-pallidotomy. These correlational analyses challenge the specificity of the switching variable and, more broadly, the validity of these qualitative measures of verbal fluency.
PMID: 14704883 [PubMed - indexed for MEDLINE]
J Clin Exp Neuropsychol. 2002 Aug;24(5):655-63
This study examined the short-term motor and cognitive sequelae of unilateral posterolateral pallidotomy for patients with intractable Parkinson's Disease (PD). Unique to this study was the inclusion of electronic motor steadiness instrumentation among pre- and postsurgical assessment procedures. Fifteen PD patients underwent right-sided surgery and 10 underwent left-sided surgery; patients were evaluated 1 month presurgery and approximately 3 months postsurgery. Motorically, there were no significant changes in grooved pegboard or maze-drawing performances, but patients evidenced significantly improved steadiness, particularly in the hand contralateral to the side of surgery. Cognitively, there were no significant decrements on postsurgery composite variables comprised of well-known tests of attention, executive functioning, delayed memory or recognition memory; these findings were similar for patients with either left- or right-sided surgery. There was, however, a significant change in language abilities among a subset of patients. This change was evident in the decline in verbal fluency in PD patients who underwent left-sided pallidotomy, a finding that has consistently emerged in pallidotomy outcome studies. This decline is discussed in terms of evidence that suggests that the basal ganglia consist of several separate, but parallel circuits, some of which are important for cognition.
PMID: 12187448 [PubMed - indexed for MEDLINE]
Health Psychol. 1997 Nov;16(6):515-20
Authors: Stetson BA, Rahn JM, Dubbert PM, Wilner BI, Mercury MG
The effects of stress on exercise behavior in community-residing women exercising on their own were assessed. Participants (N = 82) completed a background questionnaire and kept exercise diaries and Weekly Stress Inventories (P. J. Brantley, G. N. Jones, E. Boudreax, & S. L. Catz, 1997) for 8 consecutive weeks. During weeks with a high frequency of stressful events, participants exercised for less time and reported lower self-efficacy for meeting upcoming exercise goals. During weeks of high perceived stress, participants exercised significantly fewer days, omitted more planned exercise sessions, were less satisfied with their exercise, and had lower self-efficacy for meeting exercise goals. Findings suggest that perceptions of stressful events and cognitive reactions to missed exercise may play a significant role in mediating exercise behavior and support the view of exercise relapse as an ongoing process.
PMID: 9386996 [PubMed - indexed for MEDLINE]
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